Abstract

▴ The progestogen dienogest exhibits highly selective binding to the progesterone receptor. It has high progestational and significant antiandrogenic activity, but only moderate antigonadotrophic activity. ▴ Dienogest inhibits ovulation, produces secretory transformation of the endometrium and has antiproliferative effects. ▴ Oral dienogest 2 mg/day plus… (More)
DOI: 10.2165/00003495-199856050-00007