Dienogest: A New Therapeutic Agent for the Treatment of Endometriosis

@article{Harada2010DienogestAN,
  title={Dienogest: A New Therapeutic Agent for the Treatment of Endometriosis},
  author={Tasuku Harada and Fuminori Taniguchi},
  journal={Women's Health},
  year={2010},
  volume={6},
  pages={27 - 35}
}
Dienogest (DNG), a progestin of 19-nortestosterone derivative, has good oral bioavailability and is highly selective for progesterone receptors. Owing to its antiovulatory, antiproliferative activities in endometrial cells, and its inhibitory effects on the secretion of cytokines, DNG is expected to be an effective treatment for endometriosis. Progesterone receptor-binding affinity is higher for DNG than for progesterone. Several pilot studies demonstrated that after 24 weeks of DNG treatment… 

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