Diencephalic and brainstem mechanisms in migraine

@article{Akerman2011DiencephalicAB,
  title={Diencephalic and brainstem mechanisms in migraine},
  author={Simon Akerman and Philip Robert Holland and Peter J. Goadsby},
  journal={Nature Reviews Neuroscience},
  year={2011},
  volume={12},
  pages={570-584}
}
Migraine is a common and complex brain disorder. Although it is clear that head pain is a key manifestation of the disorder for most patients, what drives the activation of neuronal pain pathways in susceptible patients is less obvious. There is growing evidence that migraine pathophysiology may, in part, include dysfunction of subcortical structures. These include diencephalic and brainstem nuclei that can modulate the perception of activation of the trigeminovascular system, which carries… 

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