Die frühzeitige Elimination der Amanita Toxine in der Therapie der Knollenblätterpilzvergiftung

@article{Langer2005DieFE,
  title={Die fr{\"u}hzeitige Elimination der Amanita Toxine in der Therapie der Knollenbl{\"a}tterpilzvergiftung},
  author={M. Langer and S. Vesconi and G. Iapichino and D. Costantino and D. Radrizzani},
  journal={Klinische Wochenschrift},
  year={2005},
  volume={58},
  pages={117-123}
}
SummaryIn a 3 year period (1975–77) 50 patients have been admitted to the I.C.U. of Polyclinic Hospital of Milan for poisoning from mushrooms of Amanita genus. In 47 cases the diagnosis was confirmed “a posteriori” by serum or urinary detection of amatoxins and/or by clinical evidence of typical liver injury.Besides the symptomatologic support, the therapeutic treatment included combined removal procedures, such as peritoneal dialysis, plasmapheresis, forced diuresis.The detection by… Expand
4 Citations
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The physio-pathological features and the clinical picture of amatoxin poisonings are described, as the basis for diagnosis and therapeutic decisions, and the treatment schedule proposed is analyzed. Expand
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Two suggestions may be derived for the therapy of Amanita intoxication in man, detection in the urine of amatoxins 2 or 3 days after mushroom ingestion points to an ongoing amatoxin absorption or reabsorption from the intestine, and should lead to therapy with adsorbents and, in the absence of diarrhea, with laxatives. Expand
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Therapeutic plasma exchange has several unique characteristics that allow it to be a potentially effective therapy in rapidly achieving this goal and recent data suggest that TPE may also be effective in the therapy of patients receiving biologic treatments who develop life‐threatening complications due to therapy. Expand

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