Die Chemie der Blutgerinnung

@article{MorawitzDieCD,
  title={Die Chemie der Blutgerinnung},
  author={Prof. P. Morawitz},
  journal={Ergebnisse der Physiologie},
  volume={4},
  pages={307-422}
}
  • P. Morawitz
  • Published 1 December 1905
  • Chemistry
  • Ergebnisse der Physiologie

The tissue factor pathway: how it has become a "prima ballerina".

Exposure of blood in vitro to a negatively charged surface such as glass triggers coagulation not by releasing TF but by activating the plasma protein, factor XII (Hageman factor) (6).

Effect of fat on the vitamin K requirement of the chick.

In these experiments, the vitamin K status of chicks was measured by determining the blood "prothromMn time" by the method of Quick (1936) as modified by Almquist (1941), which indicates that lipaemia per se did not cause the shortening of " prothrombin time" observed after feeding a high-fat diet.

Encephalomalacia/gliosis, deep venous thrombosis, and cancer in Arg393His antithrombin Hanoi and the potential impact of the β-amyloid precursor protein (APP) on thrombosis and cancer

This article focuses on the “two way association” between cancer and thrombosis in which venous thromboembolism can be both a presenting sign and a complication of cancer and the construction of expression vectors for HGprt and APP, with or without the glycosyl-phosphatidylinositol (GPI) anchor.

From ancient leech to direct thrombin inhibitors and beyond: New from old.

Structure and function of factor X: properties, activation, and activity in prothrombinase. A retrospective in a historical context

  • C. Jackson
  • Biology
    Journal of Thrombosis and Thrombolysis
  • 2021
The evolution of the authors' understanding of the formation of thrombin from the postulated thrombokinase of Morawitz to activated Factor X and prothrombinase occurred during a period of nearly 100 years and the roles of phospholipid surfaces, the accessory factor, Factor V and its activated form have been clarified.

A History of Coagulopathy in Liver Disease: Legends and Myths

Watch an interview with the author.

Calcium functioned carboxymethylated cotton fabric for hemostatic wound dressing

Cal calcium functioned carboxymethylated cotton fabric (MCF-Ca) conveniently prepared by car boxymethylation of cotton fabrics followed by treatment with calcium chloride solution could serve as an effective hemostatic wound dressing for patients with uncontrolled or massive hemorrhage.

Beyond thrombosis: the impact of tissue factor signaling in cancer

The regulation of TF expression, mechanisms of TF signaling, their pathological consequences, and how it is being targeted in experimental cancer therapeutics are reviewed in detail.

Aspects of platelet transfusions and the association between routine coagulation tests and outcome

Study III, a retrospective cohort study, showed that prolonged APTT and increased PT-INR on admission to the ICU correlated with increased mortality in patients with severe sepsis or septic shock and the need for vasopressors and renal replacement therapy.
...

References

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On the effect of Peptone on the Clotting of Blood and Lymph

This short preliminary paper records an experiment showing that slow injection of peptone may lead to blood which clots normally, lymph which does not clot, and a proof that the lymph is completely dependent on the blood and produced therefrom by a physical diffusion.

III. On the leucocytes of peptone and other varieties of liquid extravascular blood

  • A. Wright
  • Medicine
    Proceedings of the Royal Society of London
  • 1893
The results of these enumerations of white blood corpuscles in the different varieties of extravascular blood are proposed to be reported here, and the bearing of the results obtained in the case of peptone blood is direct attention.