Die Another Day: Inhibition of Cell Death Pathways by Cytomegalovirus

@article{Brune2017DieAD,
  title={Die Another Day: Inhibition of Cell Death Pathways by Cytomegalovirus},
  author={Wolfram Brune and Christopher E Andoniou},
  journal={Viruses},
  year={2017},
  volume={9}
}
  • Wolfram Brune, Christopher E Andoniou
  • Published 2017
  • Biology, Medicine
  • Viruses
  • Multicellular organisms have evolved multiple genetically programmed cell death pathways that are essential for homeostasis. The finding that many viruses encode cell death inhibitors suggested that cellular suicide also functions as a first line of defence against invading pathogens. This theory was confirmed by studying viral mutants that lack certain cell death inhibitors. Cytomegaloviruses, a family of species-specific viruses, have proved particularly useful in this respect… CONTINUE READING

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