Dictyostelium nucleomorphin is a member of the BRCT-domain family of cell cycle checkpoint proteins.

@article{Myre2004DictyosteliumNI,
  title={Dictyostelium nucleomorphin is a member of the BRCT-domain family of cell cycle checkpoint proteins.},
  author={Michael A. Myre and Danton H. O'Day},
  journal={Biochimica et biophysica acta},
  year={2004},
  volume={1675 1-3},
  pages={192-7}
}
A search of the Dictyostelium genome project database (http://dictybase.org/db/cgi-bin/blast.pl) with nucleomorphin, a protein that regulates the nuclear number, predicted it to be encoded by a larger gene containing a putative breast cancer carboxy-terminus domain (BRCT). Using RT-PCR, Northern and Western blotting we have identified a differentially expressed, 2318 bp cDNA encoding a protein isoform of Dictyostelium NumA with an apparent molecular weight of 70 kDa that we have called NumB. It… CONTINUE READING