• DOI:10.1016/0014-5793(82)80941-1
Corpus ID: 26423451

Dictyostelium discoideum: a useful model system to evaluate the function of queuine and of the Q‐family of tRNAs

@article{Ott1982DictyosteliumDA,
  title={Dictyostelium discoideum: a useful model system to evaluate the function of queuine and of the Q‐family of tRNAs},
  author={G. Ott and H. Kersten and S. Nishimura},
  journal={FEBS Letters},
  year={1982},
  volume={146}
}

• G. Ott, H. Kersten, S. Nishimura
• Published 1982
• Biology, Medicine
• FEBS Letters

The nucleoside queuosine (Q) is found in the first position of the anticodon of tRNATy r, tRNA His, tRNAAsp and tRNA Asn of eubacteria and eukaryotes except yeast [1]. In eukaryotes queuine is inserted into the tRNAs in exchange for guanine by the enzyme queuine: guanine tRNAtransglycosylase [2,3]. Experiments with germ-free mice, fed on queuine-free diet, showed that mice do not synthesize queuine de novo [4,5]. The modification queuine in the Q-family of tRNA was found to be incomplete in… Expand

View on Wiley

febs.onlinelibrary.wiley.com

Save to Library

Create Alert

Cite

Launch Research Feed