Dictyostelium DdCP224 is a microtubule-associated protein and a permanent centrosomal resident involved in centrosome duplication.

@article{Grf2000DictyosteliumDI,
  title={Dictyostelium DdCP224 is a microtubule-associated protein and a permanent centrosomal resident involved in centrosome duplication.},
  author={Ralph O Gr{\"a}f and Christine Daunderer and Manfred Schliwa},
  journal={Journal of cell science},
  year={2000},
  volume={113 ( Pt 10)},
  pages={1747-58}
}
A cDNA encoding a 224-kDa Dictyostelium discoideum centrosomal protein (DdCP224) was isolated by immunoscreening. DdCP224 was detected at the centrosome and, more weakly, along microtubules throughout the entire cell cycle. Centrosomal localization does not require microtubules, suggesting that DdCP224 is a genuine centrosomal component. DdCP224 exhibits sequence identity to a weakly conserved class of microtubule-associated proteins including human TOGp and yeast Stu2p. Stu2p has a size of… CONTINUE READING
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