Dictionary of protein secondary structure: Pattern recognition of hydrogen‐bonded and geometrical features

@article{Kabsch1983DictionaryOP,
  title={Dictionary of protein secondary structure: Pattern recognition of hydrogen‐bonded and geometrical features},
  author={Wolfgang Kabsch and Christian A. Sander},
  journal={Biopolymers},
  year={1983},
  volume={22}
}
For a successful analysis of the relation between amino acid sequence and protein structure, an unambiguous and physically meaningful definition of secondary structure is essential. We have developed a set of simple and physically motivated criteria for secondary structure, programmed as a pattern‐recognition process of hydrogen‐bonded and geometrical features extracted from x‐ray coordinates. Cooperative secondary structure is recognized as repeats of the elementary hydrogen‐bonding patterns… 

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...

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