Diclofenac metabolic profile followingin vitro percutaneous absorption through viable human skin

Abstract

The extent of metabolism of diclofenac sodium in excised viable human skin was investigated using combination HPLC and radioactivity assay. In an earlier diffusion experiment using anin vitro flow-through diffusion system, radiolabelled diclofenac sodium in either lotion (PennsaidPR) or aqueous solution was applied to viable human skin, either as single… (More)
DOI: 10.1007/BF03190043

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@article{Tanojo1999DiclofenacMP, title={Diclofenac metabolic profile followingin vitro percutaneous absorption through viable human skin}, author={Hanafi Tanojo and Ronald C. Wester and J. Zev Shainhouse and Howard Ira Maibach}, journal={European Journal of Drug Metabolism and Pharmacokinetics}, year={1999}, volume={24}, pages={345-351} }