Diclofenac exposure alter the expression of PXR and its downstream target genes in mosquito fish (Gambusia affinis).

Abstract

As one of widely used drugs, Diclofenac (DCF) recently has been universally detected in aquatic environment and some negative effects derived from DCF exposure to mammals have been also reported. However, studies about its potential deleterious effects on non-target organisms like fish still require more investigation. In this study an ubiquitous small… (More)
DOI: 10.1016/j.scitotenv.2017.10.305

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