• DOI:10.1007/s00705-017-3565-0
• Corpus ID: 254048941

Dicipivirus (family Picornaviridae) in wild Northern white-breasted hedgehog (Erinaceus roumanicus)

@article{Reuter2017DicipivirusP,
  title={Dicipivirus (family Picornaviridae) in wild Northern white-breasted hedgehog (Erinaceus roumanicus)},
  author={G{\'a}bor Reuter and {\'A}kos Boros and G{\'a}bor F{\"o}ldv{\'a}ri and S{\'a}ndor Szekeres and R{\'o}bert M{\'a}tics and Beatrix Kapusinszky and Eric L. Delwart and P{\'e}ter Pankovics},
  journal={Archives of Virology},
  year={2017},
  volume={163},
  pages={175 - 181}
}

• G. Reuter, Á. Boros, +5 authors P. Pankovics
• Published 22 September 2017
• Biology
• Archives of Virology

Using random amplification and high-throughput sequencing technology a novel picornavirus with dicistronic genome organization and genetically related to canine picodicistrovirus (genus Dicipivirus, family Picornaviridae) was identified and characterized in Northern white-breasted hedgehogs. Hedgehog dicipivirus (hedgehog/H14/2015/HUN, MF188967) was detected in 15 (75%) of 20 faecal specimens by RT-PCR with high viral loads (up to 8.2x108 genomic copies/ml faeces). Hedgehog dicipivirus RNA was also identified in blood, ear skin, abdominal muscle and liver tissues. While the general dicistronic genome organization of hedgehog/H14/2015/HUN is similar to canine picodicistrovirus (5’UTR-P1-IGR-P2/P3-3UTR) there are some unique genome characteristics within the untranslated regions, especially in the functional IRES elements. This study reports the putative second member of the genus Dicipivirus, in a novel host species.