Dichotomy of action-potential backpropagation in CA1 pyramidal neuron dendrites.

@article{Golding2001DichotomyOA,
  title={Dichotomy of action-potential backpropagation in CA1 pyramidal neuron dendrites.},
  author={Nace L Golding and William L. Kath and Nelson Spruston},
  journal={Journal of neurophysiology},
  year={2001},
  volume={86 6},
  pages={
          2998-3010
        }
}
In hippocampal CA1 pyramidal neurons, action potentials are typically initiated in the axon and backpropagate into the dendrites, shaping the integration of synaptic activity and influencing the induction of synaptic plasticity. Despite previous reports describing action-potential propagation in the proximal apical dendrites, the extent to which action potentials invade the distal dendrites of CA1 pyramidal neurons remains controversial. Using paired somatic and dendritic whole cell recordings… CONTINUE READING

Citations

Publications citing this paper.
SHOWING 1-10 OF 116 CITATIONS, ESTIMATED 76% COVERAGE

Frequency-Dependent Changes in NMDAR-Dependent Synaptic Plasticity

  • Front. Comput. Neurosci.
  • 2011
VIEW 6 EXCERPTS
CITES BACKGROUND & METHODS
HIGHLY INFLUENCED

Roles of IA and morphology in action potential propagation in CA1 pyramidal cell dendrites

  • Journal of Computational Neuroscience
  • 2007
VIEW 18 EXCERPTS
CITES BACKGROUND & RESULTS
HIGHLY INFLUENCED

A Glutamatergic Spine Model to Enable Multi-Scale Modeling of Nonlinear Calcium Dynamics

  • Front. Comput. Neurosci.
  • 2018
VIEW 5 EXCERPTS
CITES BACKGROUND & RESULTS
HIGHLY INFLUENCED

Compartmental neural simulations with spatial adaptivity

  • Journal of Computational Neuroscience
  • 2008
VIEW 9 EXCERPTS
CITES METHODS, RESULTS & BACKGROUND

FILTER CITATIONS BY YEAR

2002
2019

CITATION STATISTICS

  • 26 Highly Influenced Citations

References

Publications referenced by this paper.
SHOWING 1-10 OF 54 REFERENCES

Calcium-dependent persistent facilitation of spike backpropagation in the CA1 pyramidal neurons.

  • The Journal of neuroscience : the official journal of the Society for Neuroscience
  • 2000
VIEW 2 EXCERPTS