Dichotomy between immunoglobulin synthesis by cells in gut and blood of patients with hypogammaglobulinaemia.

Abstract

Eleven of fifteen patients with late-onset hypogammaglobulinaemia were found to have significant numbers of immunoglobulin-containing cells in the lamina propria of the gut. In six of them typical plasma cells were detected. In contrast the blood lymphocytes of only two of these patients could be induced to synthesise immunoglobulin by stimulation with… (More)

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@article{Broom1975DichotomyBI, title={Dichotomy between immunoglobulin synthesis by cells in gut and blood of patients with hypogammaglobulinaemia.}, author={Bradley Broom and Emilio G{\'o}mez de la Concha and Arvie Webster and G. Loewi and Geoffrey L. Asherson}, journal={Lancet}, year={1975}, volume={2 7928}, pages={253-6} }