Dichotomous effects of chronic intermittent hypoxia on focal cerebral ischemic injury.

@article{Jackman2014DichotomousEO,
  title={Dichotomous effects of chronic intermittent hypoxia on focal cerebral ischemic injury.},
  author={Katherine A. Jackman and Ping Zhou and Giuseppe Faraco and Pablo M Peixoto and Christal G Coleman and Henning U. Voss and Virginia M Pickel and Giovanni Manfredi and C Iadecola},
  journal={Stroke},
  year={2014},
  volume={45 5},
  pages={1460-7}
}
BACKGROUND AND PURPOSE Obstructive sleep apnea, a condition associated with chronic intermittent hypoxia (CIH), carries an increased risk of stroke. However, CIH has been reported to either increase or decrease brain injury in models of focal cerebral ischemia. The factors determining the differential effects of CIH on ischemic injury and their mechanisms remain unclear. Here, we tested the hypothesis that the intensity of the hypoxic challenge determines the protective or destructive nature of… CONTINUE READING
Recent Discussions
This paper has been referenced on Twitter 1 time over the past 90 days. VIEW TWEETS

Citations

Publications citing this paper.
Showing 1-10 of 10 extracted citations

References

Publications referenced by this paper.

Similar Papers

Loading similar papers…