Dichloromethane metabolism and C1 utilization genes in Methylobacterium strains.

@article{Kayser2002DichloromethaneMA,
  title={Dichloromethane metabolism and C1 utilization genes in Methylobacterium strains.},
  author={Martin F Kayser and Z{\"o}hre Ucurum and St{\'e}phane Vuilleumier},
  journal={Microbiology},
  year={2002},
  volume={148 Pt 6},
  pages={1915-22}
}
The ability of methylotrophic alpha-proteobacteria to grow with dichloromethane (DCM) as source of carbon and energy has long been thought to depend solely on a single cytoplasmic enzyme, DCM dehalogenase, which converts DCM to formaldehyde, a central intermediate of methylotrophic growth. The gene dcmA encoding DCM dehalogenase of Methylobacterium dichloromethanicum DM4 was expressed from a plasmid in closely related Methylobacterium strains lacking this enzyme. The ability to grow with DCM… CONTINUE READING