Dichamanetin inhibits cancer cell growth by affecting ROS-related signaling components through mitochondrial-mediated apoptosis.
@article{Yong2013DichamanetinIC, title={Dichamanetin inhibits cancer cell growth by affecting ROS-related signaling components through mitochondrial-mediated apoptosis.}, author={Yeonjoong Yong and Susan Matthew and Jennifer A. Wittwer and L. Pan and Q. Shen and A. Kinghorn and S. Swanson and E. C. D. de Blanco}, journal={Anticancer research}, year={2013}, volume={33 12}, pages={ 5349-55 } }
BACKGROUND/AIM
Dichamanetin is a C-benzylated flavanone isolated as a major secondary metabolite from Piper sarmentosum, a plant used as a spice in Southeast Asia. This study aimed to investigate the path through which dichamanetin exerts its antiproliferative effect.
MATERIALS AND METHODS
The study of several signaling cellular components, namely, reactive oxygen species (ROS) levels, nuclear factor kappa-light-chain-enhancer of activated B cells (NF-κB) transcription factor, mitochondrial… CONTINUE READING
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