Dicer is required for proliferation, viability, migration and differentiation in corticoneurogenesis.

@article{McLoughlin2012DicerIR,
  title={Dicer is required for proliferation, viability, migration and differentiation in corticoneurogenesis.},
  author={Hayley Sarah McLoughlin and Sarah Kathryn Fineberg and Lagnajita Ghosh and Luis Tecedor and Beverly L. Davidson},
  journal={Neuroscience},
  year={2012},
  volume={223},
  pages={285-95}
}
In mice, microRNAs (miRNAs) are required for embryonic viability, and previous reports implicate miRNA participation in brain cortical neurogenesis. Here, we provide a more comprehensive analysis of miRNA involvement in cortical brain development. To accomplish this we used mice in which Dicer, the RNase III enzyme necessary for canonical miRNA biogenesis… CONTINUE READING