Dicer-1 is a key enzyme in the regulation of oogenesis in panoistic ovaries.

@article{Tanaka2012Dicer1IA,
  title={Dicer-1 is a key enzyme in the regulation of oogenesis in panoistic ovaries.},
  author={{\'E}rica Donato Tanaka and Maria-Dolors 4 Piulachs},
  journal={Biology of the cell},
  year={2012},
  volume={104 8},
  pages={
          452-61
        }
}
BACKGROUND INFORMATION In insects, the action of microRNAs (miRNAs) on oogenesis has been explored only in dipterans, which possess meroistic ovaries, a highly modified ovarian type. Here we study miRNA function in the most primitive, panoistic type of ovaries using the phylogenetically basal insect Blattella germanica (Dictyoptera, Blattellidae) as model. RESULTS Dicer-1 (Dcr1), a key enzyme in miRNA biogenesis, was depleted using RNAi. Females treated with double-stranded RNA targeting… CONTINUE READING
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