Diazinon cytotoxicity and transfer in Caco-2 cells: Effect of long-term exposure to the pesticide.


The purpose of this work was to investigate the effect of prolonged exposure to diazinon (widely used organophosphorus pesticide) on the intestinal cell-line Caco-2. Cytotoxicity of the pesticide (50μM-6mM) significantly decreased in long-term exposed (20μM, 2 months) cells, compared to untreated control cells. In long-term exposed cells, the resistance to… (More)
DOI: 10.1016/j.etap.2005.03.002


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