Diazepam inhibits proliferation of human glioblastoma cells through triggering a G0/G1 cell cycle arrest.

@article{Chen2013DiazepamIP,
  title={Diazepam inhibits proliferation of human glioblastoma cells through triggering a G0/G1 cell cycle arrest.},
  author={Jingkao Chen and Ying Ouyang and Lin Cao and Wenbo Zhu and Yuxi Zhou and Yuehan Zhou and Haipeng Zhang and Xiaoxiao Yang and Lifang Mao and Suizhen Lin and Jun Lin and Jun Yi Hu and Guangmei Yan},
  journal={Journal of neurosurgical anesthesiology},
  year={2013},
  volume={25 3},
  pages={285-91}
}
BACKGROUND Glioblastoma (GBM), the most common primary brain tumor, is the most aggressive malignancy in humans. Its rapid proliferation is a major obstacle to successful treatment. Patients with GBM often suffer from psychological disturbances associated with poor prognosis and physical discomfort. Diazepam is one of the most frequently used benzodiazepines (BZs) in cancer patients for its desirable psychotropic effects. The central effects of BZs are mediated by the activation of central BZ… CONTINUE READING
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