Diazepam and propranolol in panic disorder and agoraphobia.

  title={Diazepam and propranolol in panic disorder and agoraphobia.},
  author={Russell Noyes and David J. Anderson and John Clancy and R R Crowe and Donald J. Slymen and Mohamed M. Ghoneim and James V. Hinrichs},
  journal={Archives of general psychiatry},
  volume={41 3},
The response to diazepam and propranolol hydrochloride was compared in 21 patients who (with one exception) met DSM-III criteria for panic disorder and agoraphobia. Each drug was administered for two weeks in double-blind fashion according to a crossover design. The response to diazepam was significantly superior on all measures. By observer rating, 18 patients showed at least moderate improvement with diazepam compared with seven receiving propranolol. Panic attacks and phobic symptoms… CONTINUE READING

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