Diastolic dysfunction and left atrial enlargement as contributing factors to functional mitral regurgitation in dilated cardiomyopathy: data from the Acorn trial.

@article{Park2009DiastolicDA,
  title={Diastolic dysfunction and left atrial enlargement as contributing factors to functional mitral regurgitation in dilated cardiomyopathy: data from the Acorn trial.},
  author={Seong-Mi Park and Seung Woo Park and Grace C Casaclang-Verzosa and Steve R. Ommen and Patricia A. Pellikka and Fletcher A. Miller and Maurice Enriquez Sarano and Spencer H. Kubo and Jae Kon Oh},
  journal={American heart journal},
  year={2009},
  volume={157 4},
  pages={762.e3-10}
}
BACKGROUND Functional mitral regurgitation (MR) is commonly seen in dilated cardiomyopathy (DCM), which may result from left ventricular (LV) dilatation and alteration in the geometric relationship of mitral valve apparatus. However, not all patients with DCM show significant MR and left atrial (LA) enlargement. The aim of this study was to assess responsible factors for developing mitral valve regurgitation. METHODS Of 300 patients enrolled in the Acorn trial, baseline echocardiography… CONTINUE READING

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