Diastolic compliance of hypertrophied ventricle is not acutely altered by pharmacologic agents influencing active processes.


OBJECTIVE To test, by studying the acute effects of drugs that influence active processes, the hypothesis that in humans with marked ventricular hypertrophy, reduced chamber compliance is primarily caused by passive structural changes. DESIGN An uncontrolled (before-after) study. SETTING University Medical Center. PATIENTS Fourteen patients with… (More)


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