Diastereoselective intramolecular carbamoylketene/alkene [2 + 2] cycloaddition: enantioselective access to pyrrolidinoindoline alkaloids.

Abstract

A novel and highly diastereoselective intramolecular carbamoylketene/alkene [2 + 2] cycloaddition has been developed, and the methodology was successfully applied to the enantioselective syntheses of (-)-esermethole and Takayama's intermediate for (+)-psychotrimine. 
DOI: 10.1021/ol303204v

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Cite this paper

@article{Araki2013DiastereoselectiveIC, title={Diastereoselective intramolecular carbamoylketene/alkene [2 + 2] cycloaddition: enantioselective access to pyrrolidinoindoline alkaloids.}, author={Takaaki Araki and Tsukasa Ozawa and Hiromasa Yokoe and Makoto Kanematsu and Masahiro Yoshida and Kozo Shishido}, journal={Organic letters}, year={2013}, volume={15 1}, pages={200-3} }