Diarrhoea in general practice: when should a Clostridium difficile infection be considered? Results of a nested case-control study.

@article{Hensgens2014DiarrhoeaIG,
  title={Diarrhoea in general practice: when should a Clostridium difficile infection be considered? Results of a nested case-control study.},
  author={Marjolein P. M. Hensgens and Olaf M Dekkers and Aljosha Demeulemeester and Anton G M Buiting and Peter Bloembergen and Birgit H. B. van Benthem and Saskia le Cessie and Ed J Kuijper},
  journal={Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases},
  year={2014},
  volume={20 12},
  pages={
          O1067-74
        }
}
Clostridium difficile infections (CDIs) are frequent in hospitals, but also seem to increase in the community. Here, we aim to determine the incidence of CDI in general practice and to evaluate current testing algorithms for CDI. Three Dutch laboratories tested all unformed faeces (12,714) for C. difficile when diagnostic testing (for any enteric pathogen) was requested by a general practitioner (GP). Additionally, a nested case-control study was initiated, including 152 CDI patients and 304… CONTINUE READING
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