Diarrhea caused in gnotobiotic piglets by the reovirus-like agent of human infantile gastroenteritis.

@article{TorresMedina1976DiarrheaCI,
  title={Diarrhea caused in gnotobiotic piglets by the reovirus-like agent of human infantile gastroenteritis.},
  author={A Torres-Medina and R. Wyatt and C. A. Mebus and N. R. Underdahl and Albert Z. Kapikian},
  journal={The Journal of infectious diseases},
  year={1976},
  volume={133 1},
  pages={22-7}
}
One- to four-day-old gnotobiotic piglets were inoculated orally with a reovirus-like agent obtained from human infants with acute gastroenteritis. Diarrhea developed in the piglets two to seven days after inoculation and was reproduced for five serial passages in one sequence and for three passages in another. Nineteen of 21 inoculated piglets developed diarrhea; reovirus-like particles were observed in intestinal contents and/or fecal samples from 17 animals with illness and from two… CONTINUE READING