Diaphragm fatigue during exercise at high altitude: the role of hypoxia and workload.

  title={Diaphragm fatigue during exercise at high altitude: the role of hypoxia and workload.},
  author={M Gudjonsdottir and Lorenzo Appendini and Paolo Baderna and Andrea Purro and Antonio Patessio and Giuseppe Vilianis and Marcello Pastorelli and Stefan B. Sigurdsson and Claudio Ferdinando Donner},
  journal={The European respiratory journal},
  volume={17 4},
The effect of high altitude (HA) on exercise-induced diaphragm fatigue in normal subjects was examined. Eight normal subjects completed an incremental exercise test at sea level (SL) and at 3,325 m. Before (baseline), during, and after exercise (recovery), maximal transdiaphragm pressure (Pdi,sniff), breathing pattern, and diaphragmatic effort (PTPdi) were measured. Arterialized blood lactate was measured at baseline and during recovery. At maximal exercise (WRmax) Pdi,sniff fell to 72% and 61… CONTINUE READING


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