Diaphragm and cardiac mitochondrial creatine kinases are impaired in sepsis.

@article{Callahan2007DiaphragmAC,
  title={Diaphragm and cardiac mitochondrial creatine kinases are impaired in sepsis.},
  author={Leigh A Callahan and Gerald S. Supinski},
  journal={Journal of applied physiology},
  year={2007},
  volume={102 1},
  pages={44-53}
}
Previous studies indicate that ATP formation by the electron transport chain is impaired in sepsis. However, it is not known whether sepsis affects the mitochondrial ATP transport system. We hypothesized that sepsis inactivates the mitochondrial creatine kinase (MtCK)-high energy phosphate transport system. To examine this issue, we assessed the effects of… CONTINUE READING