Dialysis-related amyloidosis: late finding or hidden epidemic?

  title={Dialysis-related amyloidosis: late finding or hidden epidemic?},
  author={Laura M Dember and Bertrand L. Jaber},
  journal={Seminars in dialysis},
  volume={19 2},
Dialysis-related amyloidosis is a complication of end-stage renal disease (ESRD) that results from retention of beta2-microglobulin (beta2M) and its deposition as amyloid fibrils into osteoarticular tissue. The clinical manifestations usually develop after several years of dialysis dependence and include carpal tunnel syndrome, destructive arthropathy, and bone cysts and fractures. High-flux membranes, daily dialysis, and hemofiltration all would be expected to delay the onset of dialysis… CONTINUE READING
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