Dialysis-membrane-dependent reduction and adsorption of circulating hepatitis C virus during hemodialysis.

  title={Dialysis-membrane-dependent reduction and adsorption of circulating hepatitis C virus during hemodialysis.},
  author={Mari Mizuno and Terumi Higuchi and Mitsuru Yanai and Katsuo Kanmatsuse and Mariko Esumi},
  volume={91 2},
BACKGROUND/AIMS Patients on chronic hemodialysis (HD) are often infected with hepatitis C virus (HCV), a common cause of chronic liver disease. In some cases, however, decreases in the serum HCV load after HD have been documented. To better understand this phenomenon, we investigated the effects of various types of dialysis membrane on virus load in the circulation in vivo and in vitro. METHODS HCV RNA levels in patients' serum, filtrate and dialyzer membranes were analyzed semiquantitatively… CONTINUE READING


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