Diallylnitrosamine: a potent respiratory carcinogen in Syrian golden hamsters: brief communication.
@article{Althoff1977DiallylnitrosamineAP,
title={Diallylnitrosamine: a potent respiratory carcinogen in Syrian golden hamsters: brief communication.},
author={J. Althoff and C. Grandjean and B. Gold},
journal={Journal of the National Cancer Institute},
year={1977},
volume={59 5},
pages={
1569-71
}
}Diallylnitrosamine (DAN), one of the few nitrosamines tested thus far that has not induced neoplasms in rats, caused a high incidence of respiratory tract tumors in Syrian golden hamsters treated sc with single or weekly doses of the compound. The effect was dose-dependent. The nasal cavity, larynx, and trachea were the most affected by DAN; most drug-induced tumors at those sites were adenocarcinomas and papillary polyps.
Topics from this paper
14 Citations
Selective induction of nasal cavity tumors in rats by diallylnitrosamine
- Medicine
- Journal of Cancer Research and Clinical Oncology
- 2005
Structural Basis for Mutagenic Activity of N-Nitrosamines in the Salmonella Histidine Reversion Assay
- Chemistry
- 1984
- 2
Carcinogenesis in rats by asymmetric nitrosamines containing an allyl group.
- Biology, Medicine
- Cancer letters
- 1984
- 5
Carcinogenicity tests of acetoxymethylphenylnitrosamine and benzenediazonium tetrafluoroborate in Syrian hamsters.
- Chemistry, Medicine
- Cancer letters
- 1982
- 14
A possible short-term prediction of potential carcinogenicity of chemical compounds in vivo by means of a promoting activity test (PAT).
- Chemistry, Medicine
- Experimentelle Pathologie
- 1978
- 13
N,N-diethyl-4-aminoazobenzene (DEAB): acute actions with respect to possible carcinogenicity as well as the role of solvents. Morphological and pharmacological investigations.
- Chemistry, Medicine
- Experimentelle Pathologie
- 1978
- 5
Mutagenicity of aliphatic nitrosamines in Salmonella typhimurium.
- Chemistry, Medicine
- Mutation research
- 1979
- 67