Diallylnitrosamine: a potent respiratory carcinogen in Syrian golden hamsters: brief communication.

@article{Althoff1977DiallylnitrosamineAP,
  title={Diallylnitrosamine: a potent respiratory carcinogen in Syrian golden hamsters: brief communication.},
  author={J. Althoff and C. Grandjean and B. Gold},
  journal={Journal of the National Cancer Institute},
  year={1977},
  volume={59 5},
  pages={
          1569-71
        }
}
  • J. Althoff, C. Grandjean, B. Gold
  • Published 1977
  • Biology, Medicine
  • Journal of the National Cancer Institute
  • Diallylnitrosamine (DAN), one of the few nitrosamines tested thus far that has not induced neoplasms in rats, caused a high incidence of respiratory tract tumors in Syrian golden hamsters treated sc with single or weekly doses of the compound. The effect was dose-dependent. The nasal cavity, larynx, and trachea were the most affected by DAN; most drug-induced tumors at those sites were adenocarcinomas and papillary polyps. 
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