Diallyl trisulfide ameliorates myocardial ischemia–reperfusion injury by reducing oxidative stress and endoplasmic reticulum stress-mediated apoptosis in type 1 diabetic rats: role of SIRT1 activation

Abstract

Diallyl trisulfide (DATS) protects against apoptosis during myocardial ischemia-reperfusion (MI/R) injury in diabetic state, although the underlying mechanisms remain poorly defined. Previously, we and others demonstrated that silent information regulator 1 (SIRT1) activation inhibited oxidative stress and endoplasmic reticulum (ER) stress during MI/R… (More)
DOI: 10.1007/s10495-017-1378-y

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@article{Yu2017DiallylTA, title={Diallyl trisulfide ameliorates myocardial ischemia–reperfusion injury by reducing oxidative stress and endoplasmic reticulum stress-mediated apoptosis in type 1 diabetic rats: role of SIRT1 activation}, author={Liming Yu and Shu Li and Xinlong Tang and Zhi Li and Jian Zhang and Xiaodong Xue and Jinsong Han and Yu Liu and Yuji Zhang and Yong Zhang and Yinli Xu and Yang Yang and Huishan Wang}, journal={Apoptosis}, year={2017}, volume={22}, pages={942-954} }