Diallyl trisufide (DATS) suppresses high glucose-induced cardiomyocyte apoptosis by inhibiting JNK/NFκB signaling via attenuating ROS generation.

Abstract

BACKGROUND Hyperglycemia is an important risk factor for cardiovascular diseases no matter if it resulted from type I or type II diabetes mellitus. High glucose-induced generation of reactive oxygen species (ROS) can lead to diabetic cardiomyopathy. In our previous study, we showed that NADPH oxidase-related ROS-induced apoptosis is mediated via the JNK… (More)
DOI: 10.1016/j.ijcard.2012.09.080

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Cite this paper

@article{Kuo2013DiallylT, title={Diallyl trisufide (DATS) suppresses high glucose-induced cardiomyocyte apoptosis by inhibiting JNK/NFκB signaling via attenuating ROS generation.}, author={Wei-wen Kuo and Wei-Jan Wang and Cheng-Yen Tsai and Chia-Li Way and Hsi-Hsien Hsu and Li-mien Chen}, journal={International journal of cardiology}, year={2013}, volume={168 1}, pages={270-80} }