Diallyl sulfide induces apoptosis in Colo 320 DM human colon cancer cells: involvement of caspase-3, NF-κB, and ERK-2

@article{Sriram2008DiallylSI,
  title={Diallyl sulfide induces apoptosis in Colo 320 DM human colon cancer cells: involvement of caspase-3, NF-$\kappa$B, and ERK-2},
  author={N. Sriram and Srinivasan Kalayarasan and P. Ashokkumar and A. Sureshkumar and G. Sudhandiran},
  journal={Molecular and Cellular Biochemistry},
  year={2008},
  volume={311},
  pages={157-165}
}
Chemoprevention is regarded as one of the most promising and realistic approaches in the prevention of human cancer. Diallyl sulfide (DAS), an organosulfur component of garlic has been known for its chemopreventive activities against various cancers and also in recent years, numerous investigations have shown that sulfur-containing compounds induce apoptosis in multiple cell lines and experimental animals. Thus the present study was focused to elucidate the anticancerous effect and the mode of… Expand
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