Diallyl sulfide alleviates cyclophosphamide-induced nephropathic encephalopathy in rats

@article{Galal2019DiallylSA,
  title={Diallyl sulfide alleviates cyclophosphamide-induced nephropathic encephalopathy in rats},
  author={S. Galal and H. Mansour and Abeer Elkhoely},
  journal={Toxicology Mechanisms and Methods},
  year={2019},
  volume={30},
  pages={208 - 218}
}
Abstract Diallyl sulfide (DAS) is a garlic-derived organosulfur compound. The current study was planned to evaluate the protecting effects of DAS against cyclophosphamide (CP)-induced nephropathic encephalopathy. DAS (100 mg/kg) was orally administered for 4 days, 60 min after the last dose, rats were injected with CP (150 mg/kg). DAS treatment before CP significantly decreased serum urea, creatinine, sodium, potassium, calcium, blood urea nitrogen (BUN), C-reactive protein (CRP), interleukin-6… Expand
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