Diallyl disulfide suppresses growth of HL-60 cell through increasing histone acetylation and p21WAF1 expression in vivo and in vitro

Abstract

AbstractAim:To examine the differentiation induction and growth inhibition of HL-60 cells by diallyl disulfide (DADS), and its relationship with the alterations of histone acetylation and p21WAF1 expression in vitro and in vivo.Methods:Differentiation was studied by nitroblue tetrazolium (NBT) reduction of HL-60 cell in vitro. HL-60 cells 5×106 were… (More)
DOI: 10.1111/j.1745-7254.2006.00433.x

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@article{Zhao2006DiallylDS, title={Diallyl disulfide suppresses growth of HL-60 cell through increasing histone acetylation and p21WAF1 expression in vivo and in vitro}, author={Jie Zhao and Wei-guo Huang and Jie He and Hui Tan and Qian-jin Liao and Qi Su}, journal={Acta Pharmacologica Sinica}, year={2006}, volume={27}, pages={1459-1466} }