Dialdehyde sesquiterpenes and other terpenoids as vanilloids.


Selected naturally occurring unsaturated dialdehyde sesquiterpenes and related bioactive terpenoids were assayed for vanilloid-like activity. Out of the 25 compounds tested, eight inhibited completely the specific binding of [3H]resiniferatoxin by rat spinal cord membranes: binding affinities ranged from 0.6 microM for cinnamodial to 19.0 microM for… (More)


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@article{Szallasi1998DialdehydeSA, title={Dialdehyde sesquiterpenes and other terpenoids as vanilloids.}, author={Arpad Szallasi and Tam{\'a}s B{\'i}r{\'o} and Shahrzad Modarres and Luigi Garlaschelli and Marlen Petersen and Andreas Klusch and Giovanni Vidari and M Jonassohn and Salvatore De Rosa and Olov Sterner and Peter M. Blumberg and JAMES. E. KRAUSE}, journal={European journal of pharmacology}, year={1998}, volume={356 1}, pages={81-9} }