Diagnostics in Ebola Virus Disease in Resource-Rich and Resource-Limited Settings

Abstract

The Ebola virus disease (EVD) outbreak in West Africa was unprecedented in scale and location. Limited access to both diagnostic and supportive pathology assays in both resource-rich and resource-limited settings had a detrimental effect on the identification and isolation of cases as well as individual patient management. Limited access to such assays in resource-rich settings resulted in delays in differentiating EVD from other illnesses in returning travellers, in turn utilising valuable resources until a diagnosis could be made. This had a much greater impact in West Africa, where it contributed to the initial failure to contain the outbreak. This review explores diagnostic assays of use in EVD in both resource-rich and resource-limited settings, including their respective limitations, and some novel assays and approaches that may be of use in future outbreaks.

DOI: 10.1371/journal.pntd.0004948

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Cite this paper

@inproceedings{Shorten2016DiagnosticsIE, title={Diagnostics in Ebola Virus Disease in Resource-Rich and Resource-Limited Settings}, author={Robert John Shorten and Colin Stewart Brown and Michael Jacobs and Simon Rattenbury and Andrew J. R. Simpson and Stephen Mepham}, booktitle={PLoS neglected tropical diseases}, year={2016} }