Diagnostics for multiple myeloma.

  title={Diagnostics for multiple myeloma.},
  author={Etsuko Yamazaki},
  journal={[Rinsho ketsueki] The Japanese journal of clinical hematology},
  volume={57 10},
  • Etsuko Yamazaki
  • Published 2016 in
    [Rinsho ketsueki] The Japanese journal of…
Multiple myeloma (MM) has been diagnosed based on the International Myeloma Working Group (IMWG) diagnostic criteria since 2003. In 2014, the IMWG updated these diagnostic criteria to add three specific biomarkers, i.e., 1) Clonal bone marrow plasma cell percentage ≥60%; 2) Involved: uninvolved serum free light chain ratio ≥100; 3) >1 focal lesion on MRI studies, based on CRAB features (hypercalcemia, renal failure, anemia, and bone lesions). An early diagnosis of MM can be made, allowing… CONTINUE READING