Diagnostic work-up and risk stratification in X-linked dilated cardiomyopathies caused by dystrophin defects.

@article{Diegoli2011DiagnosticWA,
  title={Diagnostic work-up and risk stratification in X-linked dilated cardiomyopathies caused by dystrophin defects.},
  author={Marta Diegoli and Maurizia Grasso and Valentina Favalli and Alessandra Serio and Fabiana I. Gambarin and Catherine Klersy and Michele Pasotti and Emanuela Agozzino and Laura Scelsi and Alessandra Ferlini and Oreste Febo and Giovanni Piccolo and Luigi T Tavazzi and Jagat S. Narula and Eloisa Arbustini},
  journal={Journal of the American College of Cardiology},
  year={2011},
  volume={58 9},
  pages={925-34}
}
OBJECTIVES We sought to describe the diagnostic work-up, phenotype, and long-term evolution of dilated cardiomyopathy (DCM) associated with Dystrophin (DYS) defects. BACKGROUND X-linked DCM associated with DYS defects can be clinically indistinguishable from other types of DCM. METHODS The series comprises 436 consecutive male patients diagnosed with DCM. Patients underwent endomyocardial biopsy (EMB). Genetic testing employed multiplex polymerase chain reaction and multiple ligation… CONTINUE READING