Diagnostic value of the molecular genetic detection of the t(11;22) translocation in Ewing's tumours

@article{DockhornDworniczak1994DiagnosticVO,
  title={Diagnostic value of the molecular genetic detection of the t(11;22) translocation in Ewing's tumours},
  author={Barbara Dockhorn-Dworniczak and K U Schaefer and R. Dantcheva and Sebastian Blasius and Werner Boecker and Stefan E. G. Burdach and Sabine Strehl and Winfried Winkelmann and Frans van Valen and Heribert J{\"u}rgens},
  journal={Virchows Archiv},
  year={1994},
  volume={425},
  pages={107-112}
}
One consistent feature of the Ewing's tumour family is the presence of a balanced translocation involving band q12 and band q24 of chromosome 22 and chromosome 11. Recent cloning of the chromosome breakpoint regions of t(11;22)(q24;q12) Ewing's sarcoma translocation has revealed that the breakpoints were localized within the Ewing's sarcoma gene (EWS gene… CONTINUE READING