Diagnostic value of next-generation sequencing in an unusual sphenoid tumor.

  title={Diagnostic value of next-generation sequencing in an unusual sphenoid tumor.},
  author={Farzad Jamshidi and Erin Pleasance and Yvonne Y. Li and Yaoqing Shen and Katayoon Kasaian and Richard D. Corbett and Peter D. Eirew and Amy Lum and Pawan Pandoh and Yongjun Zhao and Jacqueline E. Schein and Richard A. Moore and Rod Rassekh and David G. Huntsman and Meg Knowling and Howard John Lim and Daniel John Renouf and Steven J. M. Jones and Marco A. Marra and Torsten O. Nielsen and Janessa Laskin and Stephen Yip},
  journal={The oncologist},
  volume={19 6},
Extraordinary advancements in sequencing technology have made what was once a decade-long multi-institutional endeavor into a methodology with the potential for practical use in a clinical setting. We therefore set out to examine the clinical value of next-generation sequencing by enrolling patients with incurable or ambiguous tumors into the Personalized OncoGenomics initiative at the British Columbia Cancer Agency whereby whole genome and transcriptome analyses of tumor/normal tissue pairs… CONTINUE READING
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