Diagnostic value of immunohistochemistry for the detection of the BRAF(V600E) mutation in papillary thyroid carcinoma: comparative analysis with three DNA-based assays.

@article{Ili2014DiagnosticVO,
  title={Diagnostic value of immunohistochemistry for the detection of the BRAF(V600E) mutation in papillary thyroid carcinoma: comparative analysis with three DNA-based assays.},
  author={Marius Ili{\'e} and Sandra Lassalle and Elodie Long-Mira and Christelle Bonnetaud and Olivier Bordone and Virginie Lespinet and Aude Lamy and Jean Christophe Sabourin and Juliette Haudebourg and Catherine Butori and Nicolas Guevara and Isabelle Peyrottes and Jean-Louis Sadoul and Alexandre Bozec and Jos{\'e} Santini and David R. Capper and Andreas von Deimling and Jean-François Emile and V{\'e}ronique J Hofman and P. Hofman},
  journal={Thyroid : official journal of the American Thyroid Association},
  year={2014},
  volume={24 5},
  pages={858-66}
}
BACKGROUND The aim of this study was to compare the detection of BRAF(V600E) by immunohistochemistry (IHC) using a mutation-specific antibody with molecular biology methods for evaluation of papillary thyroid carcinoma (PTC) patients. PATIENTS AND METHODS This study concerned 198 consecutive conventional PTC patients, of which the majority were women (133/198; 67%), with a mean age of 56 years (range 19-79 years). BRAF mutation analysis was performed using DNA-based (direct sequencing… CONTINUE READING

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References

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: a meta - analysis

S Asioli, LA Erickson, A Righi, RV Lloyd
2013

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