Diagnostic value of brain chronic black holes on T1-weighted MR images in clinically isolated syndromes.

@article{Mitjana2014DiagnosticVO,
  title={Diagnostic value of brain chronic black holes on T1-weighted MR images in clinically isolated syndromes.},
  author={R Mitjana and Mar Tintore and Maria Assunta Rocca and C Auger and Frederik Barkhof and Massimo Filippi and Chris H. Polman and Franz Fazekas and E Huerga and Xavier Montalban and Alex Rovira},
  journal={Multiple sclerosis},
  year={2014},
  volume={20 11},
  pages={1471-7}
}
BACKGROUND Non-enhancing black holes (neBHs) are more common in multiple sclerosis (MS) patients with longer disease durations and progressive disease subtypes. OBJECTIVE Our aim was to analyse the added value of neBHs in patients with clinically isolated syndromes (CISs) for predicting conversion to clinically definite MS (CDMS). METHODS Patients were classified based on the presence or absence of neBHs and on the number of Barkhof-Tintoré (B-T) criteria fulfilled. Dissemination in space… CONTINUE READING

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