Diagnostic utility of inflammatory biomarkers in asthma: exhaled nitric oxide and induced sputum eosinophil count.

@article{Fortuna2007DiagnosticUO,
  title={Diagnostic utility of inflammatory biomarkers in asthma: exhaled nitric oxide and induced sputum eosinophil count.},
  author={Ana Mar{\'i}a Fortuna and Teresa Feixas and Mercedes Gonz{\'a}lez and Pere Cas{\'a}n},
  journal={Respiratory medicine},
  year={2007},
  volume={101 11},
  pages={
          2416-21
        }
}
BACKGROUND Even though an inflammatory process is known to be the underlying cause of asthma, diagnosis is based on clinical history, reversible airway obstruction and bronchial hyperresponsiveness according to international guidelines. The fraction of exhaled nitric oxide (FE(NO)) and induced sputum eosinophil count (Eos%) have been used as non-invasive inflammatory biomarkers. OBJECTIVES The aim of this study was to compare the sensitivity and specificity of FE(NO), Eos% and spirometry and… CONTINUE READING

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