Diagnostic utility of different MRI and MR angiography measures in Fabry disease.

@article{Fellgiebel2009DiagnosticUO,
  title={Diagnostic utility of different MRI and MR angiography measures in Fabry disease.},
  author={Andreas Fellgiebel and Isabel Keller and Denise Marin and Matthias M{\"u}ller and Ingrid Schermuly and Igor Yakushev and Juliane Albrecht and H Bellh{\"a}user and Max Kinateder and Marcus Beck and Peter Stoeter},
  journal={Neurology},
  year={2009},
  volume={72 1},
  pages={63-8}
}
BACKGROUND Neurologic hallmarks of Fabry disease (FD) include small fiber neuropathy as well as cerebral micro- and macroangiopathy with premature stroke. Cranial MRI shows progressive white matter lesions (WML) at an early age, increased signal intensity in the pulvinar, and tortuosity and dilatation of the larger vessels. To unravel the most promising imaging tool for the detection of CNS involvement in FD we compared the diagnostic utility of the different MR imaging findings. METHODS… CONTINUE READING