Diagnostic utility of cerebrospinal fluid immunocytochemistry for diagnosis of feline infectious peritonitis manifesting in the central nervous system.

@article{Gruendl2017DiagnosticUO,
  title={Diagnostic utility of cerebrospinal fluid immunocytochemistry for diagnosis of feline infectious peritonitis manifesting in the central nervous system.},
  author={Stefanie Gruendl and Kaspar Matiasek and Lara Matiasek and A Fischer and Sandra Felten and Konrad Jurina and Katrin Hartmann},
  journal={Journal of feline medicine and surgery},
  year={2017},
  volume={19 6},
  pages={576-585}
}
Objectives The aim of the study was to evaluate whether an ante-mortem diagnosis of central nervous system (CNS) feline infectious peritonitis (FIP) is possible via immunocytochemical staining (ICC) of feline coronavirus antigen (FCoV) within macrophages of cerebrospinal fluid (CSF). Methods Prospectively, CSF samples of 41 cats were investigated, including cats with histopathologically confirmed FIP and neurological signs (n = 10), cats with confirmed FIP without CNS involvement (n = 11), cats… CONTINUE READING
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