Diagnostic utility of anti-Saccharomyces cerevisiae antibody (ASCA) and Interferon-γ assay in the differential diagnosis of Crohn's disease and intestinal tuberculosis.

@article{Kim2011DiagnosticUO,
  title={Diagnostic utility of anti-Saccharomyces cerevisiae antibody (ASCA) and Interferon-γ assay in the differential diagnosis of Crohn's disease and intestinal tuberculosis.},
  author={You Sun Kim and Youngho Kim and Won Ho Kim and Joo Sung Kim and Young Sook Park and Suk Kyun Yang and Byong Duk Ye and Byung Ik Jang and Sung Ae Jung and Yoon Tae Jeen and Jae Hee Cheon and Yong Sung Choi and Jai Hyun Choi and Beom Jin Kim and Chang Hwan Choi and Dong - Soo Han},
  journal={Clinica chimica acta; international journal of clinical chemistry},
  year={2011},
  volume={412 17-18},
  pages={1527-32}
}
BACKGROUND Differential diagnosis of Crohn's disease (CD) from intestinal tuberculosis (ITB) is challenging. Anti-Saccharomyces cerevisiae antibody (ASCA) is a specific serological marker for CD and INF-gamma assay (QuantiFERON-TB gold test, QFT) is a good supplementary diagnostic tool for ITB. We evaluated the clinical usefulness of ASCA and QFT for differential diagnosis of CD from ITB in Korean adults. METHODS A total of 147 patients suspected to have ITB or CD were prospectively enrolled… CONTINUE READING